From Chapter 1:
In the Wallace Collection at Hertford House is a pouch or case labelled as having belonged to and been used by Sir Walter Raleigh. This pouch contains several clay pipes. It was perhaps this same pouch or case which once upon a time figured in Ralph Thoresby's museum at Leeds, and is described by Thoresby himself in his "Ducatus Leodiensis," 1715. Curiously enough, a few years ago when excavations were being made around the foundations of Raleigh's house at Youghal a clay pipe-bowl was dug up which in size, shape, &c., was exactly like the pipes in the Wallace exhibit. Raleigh lived and no doubt smoked in the Youghal house, so it is quite possible that the bowl found belonged to one of the pipes actually smoked by him. In the garden of the Youghal house, by the way, they used to show the tree—perhaps still do so—under which Raleigh was sitting, smoking his pipe, when his servant drenched him. Thus the tradition, which, as we have seen, dates from 1708 only, has obtained two local habitations—Youghal and Durham House on the Adelphi site.

From Chapter 5:
Among the many medicinal virtues attributed to tobacco was its supposed value as a preservative from contagion at times of plague. Hearne, the antiquary, writing early in 1721, said that he had been told that in the Great Plague of London of 1665 none of those who kept tobacconists' shops suffered from it, and this belief no doubt enhanced the medical reputation of the weed. I have also seen it stated that during the cholera epidemics of 1831, 1849, and 1866 not one London tobacconist died from that disease; but good authority for the statement seems to be lacking. Hutton, in his "History of Derby," says that when that town was visited by the plague in 1665, that at the "Headless-cross ... the market-people, having their mouths primed with tobacco as a preservative, brought their provisions.... It was observed, that this cruel affliction never attempted the premises of a tobacconist, a tanner or a shoemaker." Whatever ground there may have been for the belief in the prophylactic effect of smoking, there can be no doubt that in the seventeenth century it was firmly held. Howell in one of his "Familiar Letters" dated January 1, 1646, says that the smoke of tobacco is "one of the wholesomest sents that is against all contagious airs, for it overmasters all other smells, as King James they say found true, when being once a hunting, a showr of rain drave him into a Pigsty for shelter, wher he caus'd a pipe full to Be taken of purpose." But here Mr. Howell is certainly drawing the long-bow. One cannot imagine the author of the "Counterblaste" countenancing the use of tobacco under any circumstances.