From Chapter 2:
A curious scene took place at Oxford in 1605 when King James visited the University. Two subjects were debated by learned dons before his Majesty, and one of them, at his own suggestion, was, "Whether the frequent use of tobacco is good for healthy men?" Among those who spoke were Doctors Ailworth, Gwyn, Gifford and Cheynell. The discussion, needless to say, being conducted in the presence of the author of the "Counterblaste to Tobacco," was not favourable to the herb. The King summed up in a speech which hopelessly begged the question while it contained plenty of strong denunciation. After his Majesty had spoken, one learned doctor, Cheynell, who is described by the recorder, Isaac Wake, the Public Orator of the University, as second to none of the doctors, had the courage to rise and, with a pipe held forth in his hand, to speak both wittily and eloquently in favour of tobacco from the medicinal point of view, praising it to the skies, says Wake, as of virtue beyond all other remedial agents. His wit pleased both the King and the whole assembly, whom it moved to laughter; but when he had finished, his Majesty made a lengthy rejoinder in which he said some curious things. He objected to the medicinal use of tobacco, and quite agreed with previous speakers that such a use must have arisen among Barbarians and Indians, who he went on to say had as much knowledge of medicine as they had of civilized customs. If, he argued, there were men whose bodies were benefited by tobacco-smoke, this did not so much redound to the credit of tobacco, as it did reflect upon the depraved condition of such men, that their bodies should have sunk to the level of those of Barbarians so as to be affected by remedies such as were effective on the bodies of Barbarians and Indians! His Majesty kindly suggested that doctors who believed in tobacco as a remedial agent should take themselves and their medicine of pollution off to join the Indians.

From Chapter 7:
Throughout the eighteenth century the use of tobacco for smoking was largely confined to the middle and humbler classes of society. To smoke was characteristic of the "cit," of the country squire, of the clergy (especially of the country parsons), and of those of lower social status. But at the same time it must be borne in mind that then, as since, the dictates of fashion and the conventions of society were little regarded by many artists and men of letters.

In the preceding chapter I quoted from Addison's diary of a retired tradesman in the Spectator of 1712. The periodical publications of a generation or so later paid the great essayist the flattery of imitation in this respect as in others. In the Connoisseur of George Colman and Bonnell Thornton, for instance, there is, in 1754, the description of a citizen's Sunday. The good man, having sent his family to church in the morning, goes off himself to Mother Redcap's, a favourite tavern—suburban in those days—or house of call for City tradesmen. There he smokes half a pipe and drinks a pint of ale. In the evening at another tavern he smokes a pipe and drinks two pints of cider, winding up the inane day at his club, where he smokes three pipes before coming home at twelve to go to bed and sleep soundly.