From Chapter 4:
From the various entries in the "Diary" relating to the purchase of tobacco, it seems clear that there was no shop in Exeter devoted specially or exclusively to the sale of the weed. Hayne bought his supplies from four of the leading goldsmiths of the city, who can be identified by the fact that he had dealings with them in their own special wares, also from two drapers, one grocer, and four other tradesmen (on a single occasion each) whose particular occupations are unknown.

From Chapter 6:
But so early as 1655 there is a sign of change of custom—a change, that is, in the direction of restricting and limiting the hitherto unbounded freedom granted to the use of tobacco. The London Society of Apothecaries on August 15, 1655, held a meeting for the election of a Master and an Upper Warden; and from the minutes of this meeting we learn that by general consent it was forbidden henceforward to smoke in the Court Room while dining or sitting, under penalty of half a crown.